A new cycloartane triterpenoid glycoside from Souliea vaginata

Nat Prod Res. 2017 Nov;31(21):2484-2490. doi: 10.1080/14786419.2017.1314283. Epub 2017 Apr 13.

Abstract

One new cycloartane triterpenoid glycoside, soulieoside Q (1), together with four known compounds (2-5) were isolated from the ethanolic extract of the rhizomes of Souliea vaginata Maxim. The structure of the new compound was determined by extensive spectroscopic analysis including 1D and 2D NMR and HRESIMS, as well as chemical methods. Compound 1 was evaluated for its cytotoxic activities against HepG2 and A549 cancer cell lines.

Keywords: Ranunculaceae; Souliea vaginata; cycloartane triterpenoid glycoside.

MeSH terms

  • Actaea / chemistry*
  • Antineoplastic Agents, Phytogenic / chemistry*
  • Antineoplastic Agents, Phytogenic / pharmacology*
  • Cell Line, Tumor
  • Glycosides / chemistry
  • Hep G2 Cells
  • Humans
  • Inhibitory Concentration 50
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Plant Extracts / chemistry
  • Rhizome / chemistry
  • Triterpenes / chemistry*
  • Triterpenes / isolation & purification

Substances

  • Antineoplastic Agents, Phytogenic
  • Glycosides
  • Plant Extracts
  • Triterpenes
  • soulieoside Q
  • cycloartane