Abstract
Melanoma is a malignant tumor with high rate of metastasis and poor prognosis. How melanoma develops and how to treat it will continue to be a hot topic. This review briefly summarizes the mechanism of melanoma development and the latest progress in its treatment.
Keywords:
Genetic mutation; Melanoma; Treatment.
Copyright © 2017 Elsevier B.V. All rights reserved.
MeSH terms
-
Angiogenesis Inhibitors / adverse effects
-
Angiogenesis Inhibitors / therapeutic use*
-
Animals
-
Antineoplastic Combined Chemotherapy Protocols / adverse effects
-
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
-
Biomarkers, Tumor / genetics
-
Cancer Vaccines / therapeutic use
-
Disease Progression
-
Genetic Predisposition to Disease
-
Humans
-
Immunotherapy / adverse effects
-
Immunotherapy / methods*
-
Immunotherapy, Adoptive
-
Melanoma / blood supply
-
Melanoma / drug therapy*
-
Melanoma / genetics
-
Melanoma / immunology
-
Molecular Targeted Therapy
-
Mutation
-
Phenotype
-
Protein Kinase Inhibitors / adverse effects
-
Protein Kinase Inhibitors / therapeutic use*
-
Signal Transduction / drug effects
-
Skin Neoplasms / blood supply
-
Skin Neoplasms / drug therapy*
-
Skin Neoplasms / genetics
-
Skin Neoplasms / immunology
Substances
-
Angiogenesis Inhibitors
-
Biomarkers, Tumor
-
Cancer Vaccines
-
Protein Kinase Inhibitors