Emetine induces estrogen receptor alpha degradation and prevents 17β-estradiol-induced breast cancer cell proliferation

Cell Oncol (Dordr). 2017 Jun;40(3):299-301. doi: 10.1007/s13402-017-0322-z. Epub 2017 Mar 29.

Authors

Claudia Busonero¹, Stefano Leone¹, Filippo Acconcia²

Affiliations

¹ Department of Sciences, Section Biomedical Sciences and Technology, University Roma Tre, Viale Guglielmo Marconi, 446, I-00146, Rome, Italy.
² Department of Sciences, Section Biomedical Sciences and Technology, University Roma Tre, Viale Guglielmo Marconi, 446, I-00146, Rome, Italy. filippo.acconcia@uniroma3.it.

PMID: 28357567
DOI: 10.1007/s13402-017-0322-z

No abstract available

Publication types

Letter

MeSH terms

Antineoplastic Agents / pharmacology*
Breast Neoplasms / pathology*
Cell Proliferation / drug effects
Emetine / pharmacology*
Estradiol / pharmacology
Estrogen Receptor alpha / drug effects*
Estrogen Receptor alpha / metabolism
Female
Humans
MCF-7 Cells

Substances

Antineoplastic Agents
ESR1 protein, human
Estrogen Receptor alpha
Estradiol
Emetine