MicroRNAs Make a Difference in Cardiovascular Robustness

Rachael Bakker; Richard W Carthew

doi:10.1016/j.devcel.2017.03.009

MicroRNAs Make a Difference in Cardiovascular Robustness

Dev Cell. 2017 Mar 27;40(6):515-516. doi: 10.1016/j.devcel.2017.03.009.

Authors

Rachael Bakker¹, Richard W Carthew²

Affiliations

¹ Department of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA.
² Department of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL 60611, USA. Electronic address: r-carthew@northwestern.edu.

Abstract

Invertebrate microRNAs (miRNAs) can suppress developmental variability that is caused by environmental and genetic variation. In this issue of Developmental Cell, Kasper et al. (2017) show that zebrafish miRNAs suppress variability in cardiovascular development during embryogenesis, providing insight into the conserved link between miRNAs and robustness.

Publication types

Comment

MeSH terms

Animals
Gene Expression Regulation, Developmental
Humans
MicroRNAs / genetics*
Zebrafish / genetics*

Substances

MicroRNAs

Abstract

Publication types

MeSH terms

Substances

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