Therapeutics for Equine Gastric Ulcer Syndrome

Fereydon Rezazadeh Zavoshti; Frank M Andrews

doi:10.1016/j.cveq.2016.11.004

Therapeutics for Equine Gastric Ulcer Syndrome

Vet Clin North Am Equine Pract. 2017 Apr;33(1):141-162. doi: 10.1016/j.cveq.2016.11.004.

Authors

Fereydon Rezazadeh Zavoshti¹, Frank M Andrews²

Affiliations

¹ University of Tabriz, 29th Bahman Boulevard, Tabriz 5166616471, Iran.
² Equine Health Studies Program, Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, Skip Bertman Drive, LA 70803, USA. Electronic address: fandrews@lsu.edu.

PMID: 28325176
DOI: 10.1016/j.cveq.2016.11.004

Abstract

Equine gastric ulcer syndrome (EGUS) is an umbrella term used to describe ulcers in the nonglandular squamous and glandular mucosa, terminal esophagus, and proximal duodenum. Gastric ulcers in the squamous and glandular regions occur more often than esophageal or duodenal ulcers and likely have a different pathogenesis. At present, omeprazole is accepted globally as the best pharmacologic therapy for both regions of the stomach; however, the addition of coating agents and synthetic prostaglandins could add to its effectiveness in treatment of EGUS. Dietary and environmental management are necessary for prevention of recurrence.

Keywords: Equine; Equine gastric ulcer syndrome; Gastric ulcer; Horse; Therapeutics.

Publication types

Review

MeSH terms

Animals
Anti-Ulcer Agents / therapeutic use
Horse Diseases / drug therapy
Horse Diseases / pathology
Horse Diseases / prevention & control
Horse Diseases / therapy*
Horses
Omeprazole / therapeutic use
Proton Pump Inhibitors / therapeutic use
Stomach Ulcer / pathology
Stomach Ulcer / prevention & control
Stomach Ulcer / therapy
Stomach Ulcer / veterinary*

Substances

Anti-Ulcer Agents
Proton Pump Inhibitors
Omeprazole