Topical application of neem leaves prevents wrinkles formation in UVB-exposed hairless mice

J Photochem Photobiol B. 2017 Apr:169:161-170. doi: 10.1016/j.jphotobiol.2017.03.010. Epub 2017 Mar 14.
No abstract available

Keywords: Anti-aging; Anti-wrinkles; Ethanolic extract; Neem; Topical application.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Azadirachta / chemistry*
  • Azadirachta / metabolism
  • Collagen Type I / genetics
  • Collagen Type I / metabolism
  • Down-Regulation / drug effects
  • Down-Regulation / radiation effects
  • Male
  • Matrix Metalloproteinase 1 / genetics
  • Matrix Metalloproteinase 1 / metabolism
  • Mice
  • Mice, Hairless
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology*
  • Plant Leaves / chemistry
  • Plant Leaves / metabolism
  • Reactive Oxygen Species / metabolism
  • Skin / metabolism
  • Skin / pathology
  • Skin Aging / drug effects*
  • Skin Aging / radiation effects
  • Transcription Factor AP-1 / antagonists & inhibitors
  • Transcription Factor AP-1 / metabolism
  • Transforming Growth Factor beta1 / metabolism
  • Ultraviolet Rays*
  • Up-Regulation / drug effects
  • Up-Regulation / radiation effects

Substances

  • Collagen Type I
  • Plant Extracts
  • Reactive Oxygen Species
  • Transcription Factor AP-1
  • Transforming Growth Factor beta1
  • Matrix Metalloproteinase 1