Orodispersible films: Towards drug delivery in special populations

Int J Pharm. 2017 May 15;523(1):327-335. doi: 10.1016/j.ijpharm.2017.03.018. Epub 2017 Mar 14.

Abstract

Orodispersible films (ODF) hold promise as a novel delivery method, with the potential to deliver tailored therapies to different patient populations. This article reviews the current strides of ODF technology and some of its unmet quality and manufacturing aspects. A topic highlights opportunities and limitations of inkjet printed ODF as a population-specific drug delivery. Overall, this article aims to stimulate further research to fill the current knowledge gap between manufacturing and administration requirements of ODF targeting specific patient subpopulations such as geriatrics.

Keywords: Acceptability; Disintegration; Drop-on-demand; Inkjet printing; Orodispersible film; Substrate.

Publication types

  • Review

MeSH terms

  • Administration, Oral
  • Chemistry, Pharmaceutical
  • Drug Delivery Systems*
  • Humans
  • Ink
  • Polymers
  • Printing

Substances

  • Polymers