Follow-up of superoxide production by phagocytes in whole blood of leukaemic patients during therapy

Acta Haematol. 1988;79(1):38-40. doi: 10.1159/000205687.

Abstract

The phagocyte function of granulocytes and monocytes of whole blood was measured as superoxide production in patients treated for acute nonlymphoblastic leukaemia. The results indicate that the antileukaemic protocol used in this study did not cause a decrease of the oxidative metabolism triggered by phagocytosis and by phorbol esters.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Follow-Up Studies
  • Humans
  • Leukemia / blood*
  • Leukemia / drug therapy
  • Leukocyte Count / methods
  • Phagocytes / drug effects
  • Phagocytes / metabolism*
  • Superoxides / biosynthesis
  • Superoxides / blood*

Substances

  • Superoxides