Mycoplasma hominis periaortic abscess following heart-lung transplantation

Transpl Infect Dis. 2017 Jun;19(3). doi: 10.1111/tid.12697. Epub 2017 May 3.

Abstract

We report the first case of Mycoplasma hominis periaortic abscess after heart-lung transplantation. The absence of sternal wound infection delayed the diagnosis, but the patient successfully recovered with debridement surgeries and long-term antibiotic therapy. Owing to the difficulty in detection and the intrinsic resistance to beta-lactams, M. hominis infections are prone to being misdiagnosed and undertreated. M. hominis should be suspected in cases where conventional microbiological identification and treatment approaches fail.

Keywords: Mycoplasma hominis; extragenital infection; mediastinitis; periaortic abscess; transplantation.

Publication types

  • Case Reports

MeSH terms

  • Abscess / diagnostic imaging
  • Abscess / microbiology
  • Abscess / therapy*
  • Adult
  • Anti-Bacterial Agents / therapeutic use*
  • Bronchoscopy
  • Cardiomyopathy, Restrictive / surgery*
  • Debridement / methods
  • Dyspnea / drug therapy
  • Dyspnea / microbiology
  • Glucocorticoids / therapeutic use
  • Graft Rejection / diagnostic imaging
  • Graft Rejection / therapy
  • Heart-Lung Transplantation / adverse effects*
  • Humans
  • Hypertension, Pulmonary / surgery*
  • Levofloxacin / therapeutic use
  • Male
  • Methylprednisolone / therapeutic use
  • Minocycline / therapeutic use
  • Mycoplasma hominis / isolation & purification
  • Mycoplasma hominis / pathogenicity*
  • Mycoplasma hominis / physiology
  • Nausea / chemically induced
  • Plasmapheresis
  • Postoperative Complications / etiology
  • Postoperative Complications / therapy
  • Respiratory Insufficiency / etiology
  • Respiratory Insufficiency / therapy
  • Sternum / surgery
  • Surgical Wound Infection / diagnosis
  • Tomography, X-Ray Computed
  • Young Adult
  • beta-Lactam Resistance
  • beta-Lactamases / pharmacology
  • beta-Lactamases / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Glucocorticoids
  • Levofloxacin
  • beta-Lactamases
  • Minocycline
  • Methylprednisolone