Dithiolato-bridged nickel-iron complexes as models for the active site of [NiFe]-hydrogenases

Li-Cheng Song; Xi-Yue Yang; Meng Cao; Xiu-Yun Gao; Bei-Bei Liu; Liang Zhu; Feng Jiang

doi:10.1039/c7cc00149e

Dithiolato-bridged nickel-iron complexes as models for the active site of [NiFe]-hydrogenases

Chem Commun (Camb). 2017 Mar 30;53(27):3818-3821. doi: 10.1039/c7cc00149e.

Authors

Li-Cheng Song¹, Xi-Yue Yang², Meng Cao², Xiu-Yun Gao², Bei-Bei Liu², Liang Zhu², Feng Jiang²

Affiliations

¹ Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Nankai University, Tianjin 300071, China. lcsong@nankai.edu.cn.
² Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China.

PMID: 28287233
DOI: 10.1039/c7cc00149e

Abstract

The structural and functional modeling of the active site of [NiFe]-hydrogenases has been proved to be challenging to a great extent. Herein, we report the synthesis, structures, and some properties of the NiFe-based dicarbonyl, terminal hydride, and μ-hydroxo models for the active site of [NiFe]-hydrogenases.

MeSH terms

Catalytic Domain
Hydrogenase / chemistry
Hydrogenase / metabolism*
Iron / chemistry
Iron / metabolism*
Models, Molecular
Molecular Conformation
Nickel / chemistry
Nickel / metabolism*
Sulfhydryl Compounds / chemistry
Sulfhydryl Compounds / metabolism*

Substances

Sulfhydryl Compounds
Nickel
Iron
nickel-iron hydrogenase
Hydrogenase