This paper presents an analogue feature detector for extraction and sampling of key-points on an arterial blood pressure signal in both humans and small mammals used as human physiological models. A CMOS integrated circuit was implemented in UMC 180nm technology, utilizing the proposed sampling method to greatly reduce the number of samples necessary for meaningful reconstruction of the low bandwidth signal. This circuit was interfaced with an external ADC to fully extract the feature points, and evaluate the system performance. Over the target heart rate range of 1 to 25 Hz, the system outperformed typical home measurement tools for systole and diastole extraction.