[Spermatogenesis recovery following allogeneic transplantation of undifferentiated Sertoli cells in experimental model of bilateral abdominal cryptorchidism]

Urologiia. 2015 Dec:(6):74-81.
[Article in Russian]

Abstract

This study explores the effect of transplantation of undifferentiated Sertoli cells in the testicular tissue of an experimental animal model of bilateral abdominal cryptorchidism. Effectiveness of undifferentiated Sertoli cell transplantation was assessed after 1 and 3 months after injection. Partial restoration of seminiferous tubules was found to occur after transplantation. In a third of them germ cells of all stages of the differentiation were discovered while they were not found in the control group.

Keywords: cryptorchidism; pediatric uro-andrology; transplantation; undifferentiated Sertoli cells.

MeSH terms

  • Animals
  • Cryptorchidism* / therapy
  • Humans
  • Male
  • Models, Theoretical
  • Seminiferous Tubules
  • Sertoli Cells* / transplantation
  • Spermatogenesis*
  • Testis
  • Transplantation, Homologous