Relationship between parental hypertension and cardiometabolic risk factors in adolescents

J Clin Hypertens (Greenwich). 2017 Jul;19(7):678-683. doi: 10.1111/jch.12991. Epub 2017 Mar 1.

Abstract

This study aimed to investigate the relationship between parental hypertension and cardiometabolic risk factors in adolescents. The authors analyzed data of 554 adolescents aged 13 to 19 years from the Korean National Health and Nutrition Examination Survey 2013. The associations between parental hypertension and cardiometabolic abnormalities in adolescents were evaluated through multivariate logistic regression. Parental hypertension was noted in 16.2% of participants. The adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for overweight (OR, 2.08; 95% CI, 1.01-4.28) and obesity (OR, 2.11; 95% CI, 1.09-4.07) were significantly higher in participants with parental hypertension. The adjusted ORs for abdominal obesity (OR, 2.36; 95% CI, 1.01-5.56), high blood pressure (OR, 3.05; 95% CI, 1.19-7.78), and elevated alanine transaminase defined as >35 IU/L (OR, 2.86; 95% CI, 1.03-7.95) were significantly higher in participants with parental hypertension. Prevention of cardiometabolic risk factors should be reinforced in the offspring of hypertensive parents.

MeSH terms

  • Adolescent
  • Alanine Transaminase / analysis
  • Cardiovascular Diseases / epidemiology*
  • Cardiovascular Diseases / physiopathology
  • Cardiovascular Diseases / prevention & control
  • Cross-Sectional Studies
  • Genetic Predisposition to Disease / epidemiology
  • Humans
  • Hypertension / epidemiology*
  • Hypertension / physiopathology
  • Obesity, Abdominal / complications
  • Obesity, Abdominal / epidemiology*
  • Overweight / complications
  • Overweight / epidemiology*
  • Parents
  • Republic of Korea / epidemiology
  • Risk Factors
  • Sedentary Behavior
  • Young Adult

Substances

  • Alanine Transaminase