Cadmium Concentration in Human Autopsy Tissues

Biol Trace Elem Res. 2017 Oct;179(2):172-177. doi: 10.1007/s12011-017-0959-5. Epub 2017 Feb 20.

Abstract

The concentration of cadmium in human tissues obtained on the basis of autopsies of non-poisoned Polish people (n = 150), aged from 1 to 80 years, examined between 1990 and 2010, is presented. The following values were found in wet digested samples by flame atomic absorption spectrometry (FAAS) (mean ± SD, median, and range, μg/g of wet weight): brain 0.020 ± 0.031, 0.084, 0-0.120 (n = 41); stomach 0.148 ± 0.195, 0.084, 0-1.25 (n = 89); small intestine 0.227 ± 0.231, 0.130, 0-0.830 (n = 39); liver 1.54 ± 1.55, 1.01, 0.015-9.65 (n = 99); kidney 16.0 ± 13.2, 14.0, 0.62-61.3 (n = 91); lung 0.304 ± 0.414, 0.130, 0-1.90 (n = 25); and heart 0.137 ± 0.107, 0.140, 0.017-0.250 (n = 4). Additionally, results (n = 13 people, aged from 2 to 83 years, 63 samples) obtained by inductively coupled plasma optical emission spectrometry (ICP OES) between 2010 and 2015 are given. The obtained data on Cd concentration in the human body can be used to estimate the amounts occurring in "healthy" people and those occurring in cases of chronic or acute poisonings with Cd compounds, which are examined for forensic purposes or to assess environmental exposure levels.

Keywords: Autopsy tissues (internal organs); Cadmium; Concentration; FAAS; ICP OES.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Autopsy
  • Cadmium / analysis*
  • Cadmium / pharmacokinetics
  • Child
  • Child, Preschool
  • Environmental Exposure / analysis
  • Female
  • Humans
  • Male
  • Middle Aged
  • Poland
  • Spectrophotometry, Atomic
  • Tissue Distribution

Substances

  • Cadmium