Flavoalkaloids-Isolation, Biological Activity, and Total Synthesis

Alkaloids Chem Biol. 2017:77:85-115. doi: 10.1016/bs.alkal.2016.04.001. Epub 2016 Jun 1.

Abstract

The flavoalkaloids possess unique molecular frameworks that contain both a flavonoid and alkaloid component. Flavoalkaloids result from the convergence of distinct biosynthetic pathways, affording natural products that display a wide range of interesting biological activities that would not be expected for flavonoids or alkaloids alone. This chapter collates all the known flavoalkaloids up until early 2016, detailing their isolation, bioactivity, and successful total syntheses.

Keywords: Alkaloid; Biologically active molecules; Flavoalkaloid; Flavonoid; Natural product; Total synthesis.

MeSH terms

  • Alkaloids* / chemical synthesis
  • Alkaloids* / isolation & purification
  • Alkaloids* / pharmacology
  • Biological Products
  • Molecular Structure
  • Stereoisomerism

Substances

  • Alkaloids
  • Biological Products