Disarming pathogens: benefits and challenges of antimicrobials that target bacterial virulence instead of growth and viability

Future Med Chem. 2017 Mar;9(3):267-269. doi: 10.4155/fmc-2016-0227. Epub 2017 Feb 16.

Author

Makrina Totsika¹

Affiliation

¹ Institute of Health & Biomedical Innovation, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD 4059, Australia.

PMID: 28207349
DOI: 10.4155/fmc-2016-0227

No abstract available

Keywords: antibiotic resistance; antivirulence therapy; bacterial infection; evolution; pathogen; virulence factor.

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / chemistry
Anti-Bacterial Agents / pharmacology*
Bacteria / drug effects*
Bacteria / growth & development
Bacteria / pathogenicity*
Microbial Viability / drug effects*
Virulence / drug effects*
Virulence Factors / antagonists & inhibitors

Substances

Anti-Bacterial Agents
Virulence Factors