An Overview of Cholesterol Homeostasis

Methods Mol Biol. 2017:1583:1-6. doi: 10.1007/978-1-4939-6875-6_1.

Abstract

Cholesterol has long been implicated in diverse aspects of human health and disease. As this lipid is both vital and lethal, ensuring that its levels are kept in check is important for maintaining health. However, studying cholesterol homeostasis can be challenging due to the extreme hydrophobic nature of cholesterol and the membranous world it inhabits. This volume of Methods in Molecular Biology brings together 21 techniques covering the gamut of cholesterol homeostasis.

Keywords: Cholesterol efflux; Cholesterol sensing; Cholesterol synthesis; Cholesterol transport; Cholesterol uptake.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Membrane / metabolism*
  • Cholesterol / metabolism*
  • Homeostasis / physiology*
  • Humans

Substances

  • Cholesterol