The development of microfabricated devices that will provide high-throughput quantitative data and high resolution in a fast, repeatable and reproducible manner is essential for plant biology research. Plants have been intensely explored since the beginning of humanity, especially for medical needs. However, plant biology research is still laborious, lacking the latest technological advancements in the laboratory practices. Microfabricated tools can provide a significant contribution to plant biology research since they require small volumes of samples and reagents with minimal cost and labor. Besides, they minimize the wet lab requirements while providing a parallel measurement platform for high-throughput data. Here, we have reviewed the cutting-edge microfabricated technologies developed for plant biology research. The description of the microfabricated device components, their integration with plant science and their substitution with the conventional techniques are presented. Our discussion on the challenges and future opportunities for scientists working at the fascinating intersection between plant science and engineering concludes this study.