Ni-Catalyzed Stannylation of Aryl Esters via C-O Bond Cleavage

Yiting Gu; Rúben Martín

doi:10.1002/anie.201611720

Ni-Catalyzed Stannylation of Aryl Esters via C-O Bond Cleavage

Angew Chem Int Ed Engl. 2017 Mar 13;56(12):3187-3190. doi: 10.1002/anie.201611720. Epub 2017 Feb 10.

Authors

Yiting Gu¹, Rúben Martín^{1

2}

Affiliations

¹ Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology, Av. Països Catalans 16, 43007, Tarragona, Spain.
² ICREA, Passeig Lluïs Companys 23, 08010, Barcelona, Spain.

PMID: 28185372
DOI: 10.1002/anie.201611720

Abstract

A Ni-catalyzed stannylation of aryl esters with air- and moisture-insensitive silylstannyl reagents via Csp2 -O cleavage is described. This protocol is characterized by its wide scope, including challenging combinations, thus enabling access to versatile building blocks and orthogonal C-heteroatom bond formations.

Keywords: C−O cleavage; aryl esters; cross-coupling; nickel.

Publication types

Research Support, Non-U.S. Gov't