Immune and inflammatory response in bronchiolitis due to respiratory Syncytial Virus and Rhinovirus infections in infants

Paediatr Respir Rev. 2017 Sep:24:60-64. doi: 10.1016/j.prrv.2016.11.006. Epub 2017 Jan 16.

Abstract

Bronchiolitis is a common disease in infancy, mostly due to Respiratory Syncytial Virus and Rhinovirus. In addition to acute infection, viral bronchiolitis is responsible for sequelae including recurrent wheezing and asthma. The analysis of the viral characteristics and of the pathogenesis of the infection shows differences between the two viruses that may be helpful for the development of therapies and preventive strategies.

Keywords: Asthma; Bronchiolitis; Respiratory Syncytial Virus; Rhinovirus; Wheezing.

Publication types

  • Review

MeSH terms

  • Asthma / immunology*
  • Bronchiolitis, Viral / immunology*
  • Bronchiolitis, Viral / virology
  • Humans
  • Immunity, Cellular / immunology*
  • Immunity, Humoral / immunology*
  • Infant
  • Inflammation / immunology*
  • Picornaviridae Infections / immunology*
  • Recurrence
  • Respiratory Sounds / immunology*
  • Respiratory Syncytial Virus Infections / immunology*
  • Respiratory Syncytial Virus, Human
  • Rhinovirus