Left ventricular functional parameters by gated SPECT myocardial perfusion imaging in a Latin American country

J Nucl Cardiol. 2018 Apr;25(2):652-660. doi: 10.1007/s12350-017-0788-0. Epub 2017 Feb 2.

Abstract

Background: There is paucity of data on left ventricular (LV) functional parameters using gated SPECT myocardial perfusion imaging (MPI) from the Latin American region. This study provides detailed information in low-risk patients both at rest and during exercise.

Methods and results: We studied 90 patients (50 men) with a very low likelihood of coronary artery disease. Gated-SPECT MPI was performed with Tc-99m MIBI using a 2-day protocol, with 16 frames/R-R cycle. The LV ejection fraction and volumes were not different between the rest and post-stress images. LVEF was 68 ± 7% post-stress and 70 ± 7% at rest in women, and 62 ± 7% and 63 ± 7%, respectively, in men (P = .19, .26). LV volumes were larger in men than women (P < .01). There were no differences in most variables obtained at rest or post-stress. Transient ischemic dilatation was similar, with upper limits of 1.20 and 1.19 in women and men, respectively (P = NS).

Conclusions: These data could prove helpful for the interpretation of gated SPECT MPI data in Latin America using identical protocol as used in this study.

Keywords: Gated-SPECT; Latin America; functional parameters.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Algorithms
  • Coronary Artery Disease / diagnostic imaging
  • Electrocardiography
  • Exercise Test
  • Female
  • Gated Blood-Pool Imaging
  • Heart Ventricles / diagnostic imaging
  • Humans
  • Image Processing, Computer-Assisted
  • Male
  • Middle Aged
  • Myocardial Perfusion Imaging*
  • Retrospective Studies
  • Technetium Tc 99m Sestamibi
  • Tomography, Emission-Computed, Single-Photon*
  • Uruguay / epidemiology
  • Ventricular Dysfunction, Left / diagnostic imaging*
  • Ventricular Function, Left*

Substances

  • Technetium Tc 99m Sestamibi