Blunting CHIKV infection by keeping T cells in check

Sci Transl Med. 2017 Feb 1;9(375):eaam6567. doi: 10.1126/scitranslmed.aam6567.

Authors

Philippe Gasque^{1

2}, Marie Christine Jaffar-Bandjee^{1

2

3}

Affiliations

¹ UMR PIMIT, Processus Infectieux en Milieu Insulaire Tropical, INSERM U1187, CNRS 9192, IRD 249, Université de La Réunion, Saint Denis, Réunion.
² LICE-OI, Laboratoire d'Immunologie Clinique et Expérimentale-zone Océan Indien, CHU Félix Guyon, Saint Denis, Réunion.
³ CNR-associé arbovirus, CHU Félix Guyon, Saint Denis, Réunion.

PMID: 28148847
DOI: 10.1126/scitranslmed.aam6567

Abstract

Modulating the host immune response ameliorates arthritic disease in mice infected with chikungunya virus (Miner et al and Teo et al).

Copyright © 2017, American Association for the Advancement of Science.

Publication types

Review
Comment

MeSH terms

Abatacept
Animals
Antiviral Agents*
Arthritis*
Chikungunya Fever*
Chikungunya virus*
Mice
T-Lymphocytes

Substances

Antiviral Agents
Abatacept