Efficient OCT Volume Reconstruction From Slitlamp Microscopes

IEEE Trans Biomed Eng. 2017 Oct;64(10):2403-2410. doi: 10.1109/TBME.2017.2657884. Epub 2017 Jan 26.

Abstract

Since its introduction 25 years ago, Optical Coherence Tomography (OCT) has contributed tremendously to diagnostic and monitoring capabilities of pathologies in the field of ophthalmology. Despite rapid progress in hardware and software technology however, the price of OCT devices has remained high, limiting their use in private practice, and in screening examinations. In this paper, we present a slitlamp-integrated OCT device, built with off-the-shelf components, which can generate high-quality volumetric images of the posterior eye segment. To do so, we present a novel strategy for 3D image reconstruction in this challenging domain that allows us for state-of-the-art OCT volumes to be generated at fast speeds. The result is an OCT device that can match current systems in clinical practice, at a significantly lower cost.

MeSH terms

  • Corneal Diseases / pathology*
  • Equipment Design
  • Equipment Failure Analysis
  • Humans
  • Image Enhancement / instrumentation
  • Image Enhancement / methods*
  • Image Interpretation, Computer-Assisted / instrumentation
  • Image Interpretation, Computer-Assisted / methods
  • Organ Size
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Slit Lamp
  • Slit Lamp Microscopy / instrumentation*
  • Slit Lamp Microscopy / methods*
  • Tomography, Optical Coherence / instrumentation*
  • Tomography, Optical Coherence / methods*