Abstract
A new 5(6→7)abeo-sterol, podosterol (1), together with 20 known compounds, were isolated from the leaves of Podocarpus fleuryi. Their structures were elucidated by means of extensive spectroscopic analysis. Podosterol was assessed for its cytotoxicity against five human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7, and SW-480), and the result showed that it had no activity.
Keywords:
Podocarpaceae; Podocarpus fleuryi; abeo-sterol; podosterol.
MeSH terms
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A549 Cells
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / isolation & purification*
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Drug Screening Assays, Antitumor
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HL-60 Cells
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Humans
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Inhibitory Concentration 50
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MCF-7 Cells
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Plant Leaves / chemistry
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Sterols / chemistry
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Sterols / isolation & purification*
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Tracheophyta / chemistry*
Substances
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Antineoplastic Agents, Phytogenic
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Sterols
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podosterol