Abstract
Prostate-specific membrane antigen (PSMA) is highly expressed in prostate cancer, and the expression increases with tumor aggressiveness, metastatic disease, and recurrence. Despite its name, PSMA is also expressed in neovasculature of other tumors including lung cancer. Here, we demonstrate a case of increased PSMA expression on Ga-PSMA PET/CT in benign lung opacities and bronchiectasis in a prostate cancer patient. Thus, increased PSMA activity in the lungs may be due to both benign and malignant diseases and warrants further evaluation.
MeSH terms
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Bronchiectasis / complications
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Bronchiectasis / diagnostic imaging*
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Edetic Acid / analogs & derivatives
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Gallium Isotopes
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Gallium Radioisotopes
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Humans
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Lung Diseases / complications
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Lung Diseases / diagnostic imaging*
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Male
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Middle Aged
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Oligopeptides
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Organometallic Compounds*
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Positron Emission Tomography Computed Tomography*
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Prostatic Neoplasms / complications*
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Prostatic Neoplasms / diagnostic imaging
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Radiopharmaceuticals*
Substances
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Gallium Isotopes
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Gallium Radioisotopes
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Oligopeptides
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Organometallic Compounds
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Radiopharmaceuticals
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gallium 68 PSMA-11
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Edetic Acid