Neonatal Respiratory Failure Caused by Congenital Diffuse Intrinsic Pontine Glioma

Katie M Satrom; Rachel A Phelan; Christopher L Moertel; H Brent Clark; Dana E Johnson; Thomas N George

doi:10.1177/0883073816689640

Neonatal Respiratory Failure Caused by Congenital Diffuse Intrinsic Pontine Glioma

J Child Neurol. 2017 May;32(6):533-536. doi: 10.1177/0883073816689640. Epub 2017 Jan 24.

Authors

Katie M Satrom¹, Rachel A Phelan², Christopher L Moertel³, H Brent Clark⁴, Dana E Johnson¹, Thomas N George¹

Affiliations

¹ 1 Neonatology, Department of Pediatrics, University of Minnesota Masonic Children's Hospital, Minneapolis, MN, USA.
² 2 Pediatric Hematology-Oncology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
³ 3 Pediatric Hematology-Oncology, Department of Pediatrics, University of Minnesota Masonic Children's Hospital, Minneapolis, MN, USA.
⁴ 4 Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MN, USA.

PMID: 28116951
DOI: 10.1177/0883073816689640

Abstract

The authors present a case of diffuse intrinsic pontine glioma presenting in a newborn with stridor and respiratory distress that progressed to respiratory failure. Magnetic resonance imaging (MRI) of the brain revealed findings compatible with the diagnosis of diffuse intrinsic pontine glioma. The family pursued palliative care and postmortem examination confirmed WHO grade III astrocytoma.

Keywords: brain stem; glioma; neonatal; respiratory distress; stridor.

Publication types

Case Reports

MeSH terms

Brain Stem Neoplasms / complications*
Brain Stem Neoplasms / diagnostic imaging
Diagnosis
Glioma / complications*
Glioma / diagnostic imaging
Humans
Infant, Newborn
Magnetic Resonance Imaging
Male
Respiratory Insufficiency / diagnostic imaging
Respiratory Insufficiency / etiology*
S100 Proteins / metabolism

Substances

S100 Proteins