The Brazilian standardization of the MATRICS consensus cognitive battery (MCCB): Psychometric study

Ana Olívia Fonseca; Arthur A Berberian; Carolina de Meneses-Gaya; Ary Gadelha; Marcella de O Vicente; Keith H Nuechterlein; Rodrigo A Bressan; Acioly L T Lacerda

doi:10.1016/j.schres.2017.01.006

The Brazilian standardization of the MATRICS consensus cognitive battery (MCCB): Psychometric study

Schizophr Res. 2017 Jul:185:148-153. doi: 10.1016/j.schres.2017.01.006. Epub 2017 Jan 17.

Authors

Ana Olívia Fonseca¹, Arthur A Berberian², Carolina de Meneses-Gaya³, Ary Gadelha³, Marcella de O Vicente³, Keith H Nuechterlein⁴, Rodrigo A Bressan³, Acioly L T Lacerda³

Affiliations

¹ Universiedade Federal de Sao Paulo (Unifesp), Department of Psychiatry, Interdisciplinary Lab of Clinical Neurosciences (LiNC), and Schizophrenia Program (PROESQ), Brazil. Electronic address: anaoliviaf@hotmail.com.
² Universiedade Federal de Sao Paulo (Unifesp), Department of Psychiatry, Interdisciplinary Lab of Clinical Neurosciences (LiNC), and Schizophrenia Program (PROESQ), Brazil; Centro Universitário FIEO, Strict Sensu Educational Psychology Program, 300 UCLA Medical Plaza, Room 2240, Los Angeles, CA 90095, USA.
³ Universiedade Federal de Sao Paulo (Unifesp), Department of Psychiatry, Interdisciplinary Lab of Clinical Neurosciences (LiNC), and Schizophrenia Program (PROESQ), Brazil.
⁴ UCLA, Department of Psychiatry and Biobehavioral Sciences , 300 UCLA Medical Plaza, Room 2240, Los Angeles, CA 90095, USA; UCLA, Department Psychology, 300 UCLA Medical Plaza, Room 2240, Los Angeles, CA 90095, USA.

PMID: 28110814
DOI: 10.1016/j.schres.2017.01.006

Abstract

Objective: Translate, adapt, and validate the MATRICS Consensus Cognitive Battery (MCCB) in Brazil.

Method: The present study followed three steps: 1) translation to Portuguese, cultural adaptation, and back translation to English; 2) completion of a pilot study (N=30) conducted with the purpose of assessing whether the general comprehension of the items was clear and all participants adequately responded to the battery; 3) completion of a Reliability and Validation Study of the Brazilian version of the MCCB with 99 individuals with schizophrenia and 99 healthy subjects. All participants were administered the Structured Clinical Interview for DSM-IV (Diagnostic and Statistical Manual of Mental Disorders) and patients were also rated on the Global Assessment of Functioning (GAF) Scale and the Positive and Negative Symptoms Scale (PANSS).

Results: The results showed adequate to high levels of baseline and 4-week retest reliability, except the MSCEIT-ME; adequate internal consistency for the MSCEIT-ME for the total sample and patients group, and moderate Alpha for the health control sample; as well as evidence of convergent validity and sensitivity to differentiate performance between the groups. All the 10 MCCB measures showed the lowest learning effects.

Conclusion: Overall the Brazilian version of the MCCB showed similar results to the original North American version. Our findings provides reassurance that the MCCB is a reliable and valid measure of cognition across different countries and cultures, which is especially important to the ongoing work in attempting to discover cognition-enhancing drugs and the effects of cognitive interventions for the treatment of schizophrenia.

Keywords: Cognitive deficits; MATRICS consensus cognitive battery; Neurocognitive function; Neuropsychology; Schizophrenia.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Brazil
Cognition Disorders / diagnosis*
Cognition Disorders / etiology*
Consensus
Female
Humans
Male
Middle Aged
Neuropsychological Tests / standards*
Neuropsychological Tests / statistics & numerical data
Psychiatric Status Rating Scales
Psychometrics / methods
Psychometrics / standards*
Schizophrenia / complications*
Schizophrenic Psychology
Translating*