Increasing Antibiotic Resistance in Shigella spp. from Infected New York City Residents, New York, USA

Emerg Infect Dis. 2017 Feb;23(2):332-335. doi: 10.3201/eid2302.161203.

Abstract

Approximately 20% of Shigella isolates tested in New York City, New York, USA, during 2013-2015 displayed decreased azithromycin susceptibility. Case-patients were older and more frequently male and HIV infected than those with azithromycin-susceptible Shigella infection; 90% identified as men who have sex with men. Clinical interpretation guidelines for azithromycin resistance and outcome studies are needed.

Keywords: Antimicrobial susceptibility; MSM; Shigella; azithromycin.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / pharmacology*
  • Azithromycin / pharmacology
  • Child
  • Child, Preschool
  • Coinfection
  • Drug Resistance, Bacterial*
  • Dysentery, Bacillary / epidemiology*
  • Dysentery, Bacillary / microbiology*
  • Female
  • HIV Infections
  • Homosexuality, Male
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Middle Aged
  • New York City / epidemiology
  • Shigella / drug effects*
  • Shigella / isolation & purification
  • Young Adult

Substances

  • Anti-Bacterial Agents
  • Azithromycin