Selenium rescues orbital fibroblasts from cell death induced by hydrogen peroxide: another molecular basis for the effects of selenium in graves' orbitopathy

Endocrine. 2017 Nov;58(2):386-389. doi: 10.1007/s12020-016-1226-9. Epub 2017 Jan 17.
No abstract available

Publication types

  • Letter

MeSH terms

  • Adipose Tissue / drug effects
  • Adipose Tissue / pathology
  • Aged
  • Cell Death / drug effects
  • Cell Death / genetics
  • Cells, Cultured
  • Cytoprotection / drug effects*
  • Female
  • Fibroblasts / drug effects*
  • Fibroblasts / pathology
  • Graves Ophthalmopathy / drug therapy*
  • Graves Ophthalmopathy / pathology
  • Graves Ophthalmopathy / prevention & control
  • Humans
  • Hydrogen Peroxide / toxicity*
  • Male
  • Middle Aged
  • Orbit / drug effects*
  • Orbit / pathology
  • Primary Cell Culture
  • Selenium / pharmacology*
  • Selenium / therapeutic use
  • Signal Transduction / drug effects
  • Signal Transduction / genetics

Substances

  • Hydrogen Peroxide
  • Selenium