Paraneoplastic Cerebellar Degeneration Associated with Pelvic Liposarcoma: A Rare Case Report

Urol Int. 2018;100(3):364-367. doi: 10.1159/000452167. Epub 2017 Jan 17.

Abstract

Paraneoplastic cerebellar degeneration (PCD) is one of the most common paraneoplastic neurological syndromes characterized by the rapid development of severe cerebellar ataxia. In this report, a 23-year-old female with noticeable dizziness and gait instability was described. The enhanced CT scanning suggested the presence of a pelvic tumor. Then, PCD was established. Postoperative pathological result defined it as a liposarcoma (LS) with dedifferentiation. Interestingly, clinical symptoms disappeared after the surgical removal of the pelvic tumor. To our knowledge, this was the first case report with PCD due to LS.

Keywords: Liposarcoma; Paraneoplastic; Pelvic.

Publication types

  • Case Reports

MeSH terms

  • Brain Diseases / complications
  • Brain Diseases / physiopathology
  • Cell Differentiation
  • Cerebellum / physiopathology
  • Female
  • Humans
  • Liposarcoma / diagnostic imaging*
  • Liposarcoma / surgery*
  • Paraneoplastic Cerebellar Degeneration / diagnostic imaging*
  • Paraneoplastic Cerebellar Degeneration / surgery*
  • Pelvic Neoplasms / diagnostic imaging*
  • Pelvic Neoplasms / surgery*
  • Pelvis / pathology*
  • Tomography, X-Ray Computed
  • Young Adult