Antitubercular Marine Natural Products

Curr Med Chem. 2018;25(20):2304-2328. doi: 10.2174/0929867324666170113120221.

Abstract

Due to the importance of nature as a source of new drug candidates, the purpose of this article is to emphasize the marine natural products, which exhibit antitubercular activity, published between January 2000 and May 2016, with 138 quotations to 250 compounds obtained from marine resources. These metabolites are organized by chemical constitution and named as simple alkyl lipids derivatives, aromatics derivatives, peptides, alkaloids, terpenoids, steroids, macrolides, and polycyclic polyketides.

Keywords: Antitubercular; Mycobacterium tuberculosis; antimycobacterial; marine drugs; marine natural products; natural product derivatives..

Publication types

  • Review

MeSH terms

  • Antitubercular Agents / chemistry
  • Antitubercular Agents / metabolism
  • Antitubercular Agents / pharmacology*
  • Biological Products / chemistry
  • Biological Products / metabolism
  • Biological Products / pharmacology*
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Mycobacterium tuberculosis / drug effects*

Substances

  • Antitubercular Agents
  • Biological Products