Lung Gene Expression Analysis (LGEA): an integrative web portal for comprehensive gene expression data analysis in lung development

Thorax. 2017 May;72(5):481-484. doi: 10.1136/thoraxjnl-2016-209598. Epub 2017 Jan 9.

Abstract

'LungGENS', our previously developed web tool for mapping single-cell gene expression in the developing lung, has been well received by the pulmonary research community. With continued support from the 'LungMAP' consortium, we extended the scope of the LungGENS database to accommodate transcriptomics data from pulmonary tissues and cells from human and mouse at different stages of lung development. Lung Gene Expression Analysis (LGEA) web portal is an extended version of LungGENS useful for the analysis, display and interpretation of gene expression patterns obtained from single cells, sorted cell populations and whole lung tissues. The LGEA web portal is freely available at http://research.cchmc.org/pbge/lunggens/mainportal.html.

Keywords: Airway Epithelium; Surfactant protein; Systemic disease and lungs; TTF-1.

MeSH terms

  • Animals
  • Chromosome Mapping
  • Computational Biology / methods*
  • Gene Expression Profiling / methods*
  • Gene Expression*
  • Humans
  • Internet*
  • Lung / growth & development*
  • Mice
  • Software
  • Transcription Factors

Substances

  • Transcription Factors