Can Surgery for Inflammatory Bowel Disease be Personalized?

Curr Drug Targets. 2018;19(7):798-804. doi: 10.2174/1389450118666170105153646.

Abstract

Background: In the treatment of Inflammatory Bowel Diseases (IBD) despite advances in medical therapies, surgery has maintained a leading role in the management of complications of the disease, as well as in cases of failure of medical therapy.

Objective: discuss the possible role for a personalization in debated fields of surgical treatment of Crohn's disease and ulcerative colitis.

Conclusions: Surgery has become more and more minimally invasive, struggling for a difficult balance between guidelines and personalized treatment tailored on the single patient's need. There is no room for fixed management for surgery in IBD. A tailored approach is key to better outcome in each specific patient.

Keywords: Crohn's disease; inflammatory bowel disease; personalization; surgery; tailored surgery; ulcerative colitis..

Publication types

  • Review

MeSH terms

  • Colitis, Ulcerative / surgery*
  • Crohn Disease / surgery*
  • Digestive System Surgical Procedures / methods
  • Humans
  • Minimally Invasive Surgical Procedures / methods
  • Practice Guidelines as Topic
  • Precision Medicine / methods*