Thinking Outside the Cell: Replicating Replication In Vitro

Rhiannon R Aguilar; Jessica K Tyler

doi:10.1016/j.molcel.2016.12.019

Thinking Outside the Cell: Replicating Replication In Vitro

Mol Cell. 2017 Jan 5;65(1):5-7. doi: 10.1016/j.molcel.2016.12.019.

Authors

Rhiannon R Aguilar¹, Jessica K Tyler²

Affiliations

¹ Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA; Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, 1300 York Avenue, New York, NY 10065, USA.
² Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA. Electronic address: jet2021@med.cornell.edu.

Abstract

Benchmark studies by Yeeles et al. (2017), Kurat et al. (2017), and Devbhandari et al. (2017) have reconstituted rapid and regulated budding yeast DNA replication on naked and chromatinized templates in vitro, providing key insights into this fundamentally important process.

MeSH terms

DNA Replication*
Saccharomycetales / genetics*

Abstract

MeSH terms

Grants and funding