Current Status of Exposed Endoscopic Full-Thickness Resection and Further Development of Non-Exposed Endoscopic Full-Thickness Resection

Digestion. 2017;95(1):6-15. doi: 10.1159/000452352. Epub 2017 Jan 5.

Abstract

Endoscopic full-thickness resection (EFTR) is a procedure that makes it possible to access the lesions that are on the wall of the digestive tract via the shortest distance through the mouth. Because of the ultra-minimal invasive nature of the treatment, pure EFTR is a highly promising surgical procedure that allows the radical excision of full-thickness layers of digestive tract tumors using only a flexible endoscope. There are 2 types of EFTR methods: exposed and non-exposed. Considering the risks of contracting infection and intraperitoneal dissemination of tumor cells, non-exposed EFTR is an ideal method. However, a number of issues remain unresolved, including the method for performing a full-thickness suture under endoscopic view and the challenge of securing the operating field in the case of gastrointestinal tract collapse. Moreover, advances in the development of equipment such as full-thickness suturing devices would be helpful to make this therapeutic procedure the most minimally invasive endoscopic surgery ever.

Publication types

  • Review

MeSH terms

  • Endoscopic Mucosal Resection / methods*
  • Endoscopy, Gastrointestinal / methods*
  • Gastrointestinal Neoplasms / surgery*
  • Gastrointestinal Tract / surgery
  • Humans
  • Mouth
  • Natural Orifice Endoscopic Surgery / methods*
  • Suture Techniques / trends