Genes, epigenetics and miRNA regulation in the placenta

Daniel Vaiman

doi:10.1016/j.placenta.2016.12.026

Genes, epigenetics and miRNA regulation in the placenta

Placenta. 2017 Apr:52:127-133. doi: 10.1016/j.placenta.2016.12.026. Epub 2016 Dec 25.

Author

Daniel Vaiman¹

Affiliation

¹ Institut Cochin, INSERM U1016, CNRS UMR8104, Université Paris-Descartes, 24, rue du Faubourg St-Jacques, 75014, Paris, France. Electronic address: daniel.vaiman@inserm.fr.

PMID: 28043658
DOI: 10.1016/j.placenta.2016.12.026

Abstract

This text reviews briefly the context in which epigenetics regulate gene expression in trophoblast development and function. It is an attempt to focus on a limited number of recent papers that, according to the author, shed new light on placental development, and constitute possible trails for improving knowledge and women follow-up in pathological pregnancies.

Keywords: DNA methylation; Epigenetics; Micro-RNA; Placenta; Preeclampsia.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Animals
DNA Methylation
Epigenesis, Genetic*
Female
Gene Expression Regulation*
Humans
MicroRNAs / genetics
MicroRNAs / metabolism*
Placenta / metabolism*
Placentation / physiology*
Pregnancy

Substances

MicroRNAs