Wilms Tumor With Metastasis to the Vagina: A Case Report

Urology. 2017 Mar:101:151-153. doi: 10.1016/j.urology.2016.12.040. Epub 2016 Dec 28.

Abstract

A 12-year-old female presented with abdominal pain, night sweats, weight loss, constipation, dysmenorrhea, menorrhagia, and vaginal discharge. Examination revealed a palpable flank mass and a large tumor adherent to the anterior vaginal wall. Computed tomography scan demonstrated a 23 cm mass in the left kidney, a separate 10.8 cm pelvic mass, and metastatic disease. Biopsies were consistent with Wilms tumor. Neoadjuvant chemotherapy and a left radical nephrectomy were performed for her stage IV disease as the kidney was amiable to complete resection. The patient received radiation and resumed chemotherapy. She was doing well with improved symptoms at follow-up.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Biopsy
  • Child
  • Female
  • Humans
  • Kidney Neoplasms / pathology*
  • Kidney Neoplasms / therapy
  • Lymph Node Excision
  • Lymphatic Metastasis
  • Magnetic Resonance Imaging
  • Neoplasm Metastasis
  • Nephrectomy / methods
  • Radiotherapy, Adjuvant
  • Tomography, X-Ray Computed
  • Vaginal Neoplasms / diagnosis
  • Vaginal Neoplasms / secondary*
  • Vaginal Neoplasms / surgery
  • Wilms Tumor / diagnosis
  • Wilms Tumor / secondary*
  • Wilms Tumor / therapy

Substances

  • Antineoplastic Agents