PML-RARA mutations confer varying arsenic trioxide resistance

Protein Cell. 2017 Apr;8(4):296-301. doi: 10.1007/s13238-016-0356-4.

Authors

Dong-Mei Bai^{1

2}, Xiao-Feng Zheng^{3

4}

Affiliations

¹ State Key Lab of Protein and Plant Gene Research, Beijing, 100871, China.
² Department of Biochemistry and Molecular Biology, School of Life Sciences, Peking University, Beijing, 100871, China.
³ State Key Lab of Protein and Plant Gene Research, Beijing, 100871, China. xiaofengz@pku.edu.cn.
⁴ Department of Biochemistry and Molecular Biology, School of Life Sciences, Peking University, Beijing, 100871, China. xiaofengz@pku.edu.cn.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Substitution
Arsenicals / pharmacology*
Cell Line
Chlorides / pharmacology*
Drug Resistance, Neoplasm / genetics*
Humans
Mutation, Missense*
Oncogene Proteins, Fusion* / genetics
Oncogene Proteins, Fusion* / metabolism

Substances

Arsenicals
Chlorides
Oncogene Proteins, Fusion
promyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein
arsenic trichloride