Datasets for next-generation sequencing of DNA and RNA from urine and plasma of patients with prostate cancer

A S Nikitina; E I Sharova; S A Danilenko; O V Selezneva; T B Butusova; A O Vasiliev; A V Govorov; E A Prilepskaya; D Y Pushkar; E S Kostryukova

doi:10.1016/j.dib.2016.12.016

Datasets for next-generation sequencing of DNA and RNA from urine and plasma of patients with prostate cancer

Data Brief. 2016 Dec 14:10:369-372. doi: 10.1016/j.dib.2016.12.016. eCollection 2017 Feb.

Authors

Affiliations

¹ Federal Research and Clinical Center of Physical-Chemical Medicine, Moscow, Russia; Moscow Institute of Physics and Technology, Dolgoprudnyi, Russia.
² Federal Research and Clinical Center of Physical-Chemical Medicine, Moscow, Russia.
³ Department of Urology, Moscow State Medical Stomatological University, Moscow, Russia.

Abstract

Current prostate cancer (PCa) diagnostic tests suffer from insufficient sensitivity and specificity. Novel biomarkers that can be detected by minimally invasive methods are of a particular value. Here we provide two datasets. The first one is on the whole transcriptome profiling by RNA-seq of urine and plasma obtained from patients with PCa and benign prostatic hyperplasia (BPH). The second one represents targeted sequencing of DNA from urine and plasma of patients with PCa and BPH. Both datasets are available at NCBI Sequence Read Archive under Accession No. SRP093707 and No. SRP093842 respectively.

Keywords: Benign prostatic hyperplasia; Prostate cancer; RNA-seq; Targeted DNA sequencing; Transcriptome.