Analytical and clinical comparison of Elecsys syphilis (Roche®) - Architect syphilis TP and reformulated Architect syphilis TP (Abbott®) assay

Diagn Microbiol Infect Dis. 2017 Mar;87(3):210-212. doi: 10.1016/j.diagmicrobio.2016.12.003. Epub 2016 Dec 9.

Abstract

The performance of Elecsys Syphilis was compared to Architect Syphilis TP and Reformulated Architect Syphilis TP. The overall sensitivity and specificity were 98.4% and 99.5%, 97.7% and 97.1%, and 99.2% and 99.7% respectively. The assays are comparable and considered adequate for syphilis screening.

Keywords: Architect syphilis TP assay; EIA; Elecsys syphilis assay; Reformulated architect syphilis TP assay; Sensitivity; Specificity; Syphilis.

Publication types

  • Comparative Study

MeSH terms

  • Bacteriological Techniques / methods
  • Biological Assay
  • Hemagglutination Tests / methods*
  • Humans
  • Immunoassay / methods*
  • Polymerase Chain Reaction / methods*
  • Reagent Kits, Diagnostic
  • Retrospective Studies
  • Sensitivity and Specificity
  • Syphilis / diagnosis*
  • Treponema pallidum / immunology*

Substances

  • Reagent Kits, Diagnostic