Ultrasound speckle reduction based on fractional order differentiation

J Med Ultrason (2001). 2017 Jul;44(3):227-237. doi: 10.1007/s10396-016-0763-4. Epub 2016 Dec 23.

Abstract

Purpose: Ultrasound images show a granular pattern of noise known as speckle that diminishes their quality and results in difficulties in diagnosis. To preserve edges and features, this paper proposes a fractional differentiation-based image operator to reduce speckle in ultrasound.

Methods: An image de-noising model based on fractional partial differential equations with balance relation between k (gradient modulus threshold that controls the conduction) and v (the order of fractional differentiation) was constructed by the effective combination of fractional calculus theory and a partial differential equation, and the numerical algorithm of it was achieved using a fractional differential mask operator.

Results: The proposed algorithm has better speckle reduction and structure preservation than the three existing methods [P-M model, the speckle reducing anisotropic diffusion (SRAD) technique, and the detail preserving anisotropic diffusion (DPAD) technique]. And it is significantly faster than bilateral filtering (BF) in producing virtually the same experimental results.

Conclusions: Ultrasound phantom testing and in vivo imaging show that the proposed method can improve the quality of an ultrasound image in terms of tissue SNR, CNR, and FOM values.

Keywords: Anisotropic diffusion; Fractional order differentiation; Speckle reduction; Ultrasound image.

MeSH terms

  • Algorithms*
  • Humans
  • Kidney / diagnostic imaging
  • Liver / diagnostic imaging
  • Phantoms, Imaging
  • Ultrasonography / methods*