The influence of the successive depolymerization and polymerization of cytoskeleton components on the fibroblast shapes

Pflugers Arch. 2000 Jan;440(Suppl 1):R204-R205. doi: 10.1007/s004240000066.

Abstract

Monitoring the influence of the cytoskeleton polymers on the shape of fibroblasts, performing the experiments of repeated degradation and polymerization of microtubules and microfilaments, we found out that the presence of microtubules is necessary in order to regenerate the proper functional structure of microfilaments, and vice versa.

Keywords: Key words cell shape; actin; fibroblasts; tubulin.