Spontaneous coronary artery dissection in a young woman with polycystic ovarian syndrome

Am J Emerg Med. 2017 Jun;35(6):936.e5-936.e7. doi: 10.1016/j.ajem.2016.12.040. Epub 2016 Dec 16.

Abstract

Polycystic ovarian syndrome (PCOS) affects 4% to 12% of women in reproductive age, representing a clinical condition that could predispose to cardiovascular diseases. We report a case of a 34-year-old woman with PCOS, presenting with chest pain, onset two days before, and ST segment-elevation myocardial infarction. She was not pregnant or in a postpartum state. Subsequent cardiac angiography revealed spontaneous left anterior descending coronary artery dissections, managed by conservative approach. The patient was discharged in medical therapy after 5days. This is the first observation of spontaneous coronary artery dissection occurring in a PCOS patient.

Keywords: Acute coronary syndrome; Polycystic ovarian syndrome; Spontaneous coronary artery dissection.

Publication types

  • Case Reports

MeSH terms

  • Acute Coronary Syndrome / diagnostic imaging*
  • Acute Coronary Syndrome / drug therapy
  • Adenosine / analogs & derivatives
  • Adenosine / therapeutic use
  • Adult
  • Aspirin / therapeutic use
  • Chest Pain / diagnosis
  • Chest Pain / etiology
  • Coronary Angiography
  • Coronary Vessel Anomalies / diagnostic imaging*
  • Coronary Vessel Anomalies / drug therapy
  • Coronary Vessels / diagnostic imaging*
  • Electrocardiography
  • Female
  • Humans
  • Platelet Aggregation Inhibitors / therapeutic use
  • Polycystic Ovary Syndrome / complications*
  • Purinergic P2Y Receptor Antagonists / therapeutic use
  • Ticagrelor
  • Vascular Diseases / congenital*
  • Vascular Diseases / diagnostic imaging
  • Vascular Diseases / drug therapy

Substances

  • Platelet Aggregation Inhibitors
  • Purinergic P2Y Receptor Antagonists
  • Ticagrelor
  • Adenosine
  • Aspirin

Supplementary concepts

  • Coronary Artery Dissection, Spontaneous