Objective: To explore the allocation of resources for diseases control and prevention in Beijing CDC and to put forward related scientific evidence for improvement. Methods: To gather and comparatively analyze the human, financial and material resources of Beijing CDC reported by China Information System, from 2010 to 2015. Results: Research findings showed that on average, 1.43 CDC members served ten thousand people in Beijing in 2015, which was below the set national standard. The proportion of staff with either master/doctor degrees or senior professional titles showed an annual upward trend from 2010 to 2015 (P<0.05), the proportion was higher in the municipal CDC than that in the District CDCs, in 2015 (P<0.05). Fiscal deficit had existed for many years. The average capability for different kinds of testings did not reach the national standard. Numbers of instruments and equipment were higher than that of the national standard. The average space of Beijing CDC was 55.9 square meters/person, again had not met the nationally recommended criteria. Conclusions: The allocation of CDC human resources was significantly imbalanced in Beijing. The structure of CDC human resources should be improved. We suggested that the Full Funding Security Model' should be unified. And the average space of the Beijing CDC should meet the national standard in the years to come.