First case of Arthrographis kalrae fungemia in a patient with cystic fibrosis

Julie Denis; Marcela Sabou; Tristan Degot; Ermanno Candolfi; Valérie Letscher-Bru

doi:10.1016/j.mmcr.2016.11.002

First case of Arthrographis kalrae fungemia in a patient with cystic fibrosis

Med Mycol Case Rep. 2016 Nov 30:14:8-11. doi: 10.1016/j.mmcr.2016.11.002. eCollection 2016 Dec.

Authors

Julie Denis¹, Marcela Sabou¹, Tristan Degot², Ermanno Candolfi¹, Valérie Letscher-Bru¹

Affiliations

¹ Laboratoire de Parasitologie et de Mycologie Médicale, Hôpitaux Universitaires de Strasbourg. 1 Place de lHôpital, 67000 Strasbourg, France; Institut de Parasitologie et de Pathologie Tropicale, EA 7292, Fédération de Médecine Translationnelle, Université de Strasbourg, 3 Rue Koeberlé, 67000 Strasbourg, France.
² Service de Pneumologie, Hôpitaux Universitaires de Strasbourg.1 place de l'hôpital, 67000 Strasbourg, France.

Abstract

Arthrographis kalrae is a hyalin fungus. It is a saprophyte of the environment, mainly found in soil and compost. In recent years, cases of opportunistic infections attributed to this pathogen have been described. Our patient was a 19-year-old woman with cystic fibrosis. She presented a bacterial and fungal pulmonary colonization with Aspergillus fumigatus and Arthrographis. kalrae. After her lung transplantation, she developed an A. kalrae fungemia, treated with caspofungin 50 mg/day associated to liposomal amphotericin B i.v. 3 mg/kg/day. The patient died 8 months after her transplantation as the result of a bacterial septic shock.

Keywords: Arthrographis kalrae; Cystic fibrosis; Fungemia; Lung transplantation.