Bacteriophage-based tools: recent advances and novel applications

F1000Res. 2016 Nov 29:5:2782. doi: 10.12688/f1000research.9705.1. eCollection 2016.

Abstract

Bacteriophages (phages) are viruses that infect bacterial hosts, and since their discovery over a century ago they have been primarily exploited to control bacterial populations and to serve as tools in molecular biology. In this commentary, we highlight recent diverse advances in the field of phage research, going beyond bacterial control using whole phage, to areas including biocontrol using phage-derived enzybiotics, diagnostics, drug discovery, novel drug delivery systems and bionanotechnology.

Keywords: bacterial diagnostics; bacteriophage; biocontrol; bionanotechnology; biotechnology; phage; phage research; phage-based drug delivery.

Publication types

  • Review

Grants and funding

L. O’Sullivan is supported by a Teagasc Walsh Fellowship Ref. 2013003.