Modular fluidic resistors to enable widely tunable flow rate and fluidic switching period in a microfluidic oscillator

Electrophoresis. 2017 Apr;38(7):977-982. doi: 10.1002/elps.201600495. Epub 2017 Jan 27.

Abstract

Microfluidic systems with modular components are attractive alternatives to monolithically integrated microfluidic systems because of their flexibility. In this study, we apply the modular concept on a water-head-pressure-driven microfluidic oscillator and obtain a widely tunable flow rate and fluidic switching period. Modular fluidic resistors can be easily mounted onto and demounted from a main chip by means of plastic male connectors. The connectors enable a leak-free connection between the modular resistors and main chip (leakage pressure > 140 kPa). With modular resistors, we show independent control of the flow rate and flow switching period of the oscillator system in a wide range (2.5 s-6.4 h and 2 μL/min-2 mL/min). This modular approach can be used to enhance the flexibility of instruction-embedded microfluidic circuits in which their operational range is limited.

Keywords: Flow rate; Fluidic resistance; Microfluidic circuit; Module; Oscillation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Equipment Design
  • Food Coloring Agents / analysis
  • Food Coloring Agents / chemistry
  • Food Coloring Agents / isolation & purification
  • Microfluidic Analytical Techniques / instrumentation*
  • Models, Chemical

Substances

  • Food Coloring Agents