Whole-Genome Characterization of a Novel Human Influenza A(H1N2) Virus Variant, Brazil

Emerg Infect Dis. 2017 Jan;23(1):152-154. doi: 10.3201/eid2301.161122.

Abstract

We report the characterization of a novel reassortant influenza A(H1N2) virus not previously reported in humans. Recovered from a a pig farm worker in southeast Brazil who had influenza-like illness, this virus is a triple reassortant containing gene segments from subtypes H1N2 (hemagglutinin), H3N2 (neuraminidase), and pandemic H1N1 (remaining genes).

Keywords: Brazil; H1N2v; influenza; influenza A virus; reassortment; subtypes; viruses; whole-genome characterization.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Animal Husbandry
  • Animals
  • Brazil
  • Female
  • Genome, Viral*
  • Hemagglutinin Glycoproteins, Influenza Virus / genetics*
  • Humans
  • Influenza A Virus, H1N1 Subtype / genetics
  • Influenza A Virus, H1N1 Subtype / isolation & purification
  • Influenza A Virus, H1N2 Subtype / genetics*
  • Influenza A Virus, H1N2 Subtype / isolation & purification
  • Influenza A Virus, H3N2 Subtype / genetics
  • Influenza A Virus, H3N2 Subtype / isolation & purification
  • Influenza, Human / diagnosis
  • Influenza, Human / virology
  • Neuraminidase / genetics*
  • Orthomyxoviridae Infections / veterinary*
  • Orthomyxoviridae Infections / virology
  • Reassortant Viruses / genetics*
  • Reassortant Viruses / isolation & purification
  • Swine
  • Swine Diseases / virology*
  • Workforce

Substances

  • Hemagglutinin Glycoproteins, Influenza Virus
  • Neuraminidase