Uterine transplantation: a systematic review

Clinics (Sao Paulo). 2016 Nov 1;71(11):679-683. doi: 10.6061/clinics/2016(11)10.

Abstract

Up to 15% of the reproductive population is infertile, and 3 to 5% of these cases are caused by uterine dysfunction. This abnormality generally leads women to consider surrogacy or adoption. Uterine transplantation, although still experimental, may be an option in these cases. This systematic review will outline the recommendations, surgical aspects, immunosuppressive drugs and reproductive aspects related to experimental uterine transplantation in women.

Publication types

  • Systematic Review

MeSH terms

  • Animals
  • Female
  • Humans
  • Immunosuppression Therapy
  • Immunosuppressive Agents / administration & dosage
  • Infertility, Female / surgery*
  • Models, Animal
  • Pregnancy
  • Uterus / drug effects
  • Uterus / immunology
  • Uterus / transplantation*

Substances

  • Immunosuppressive Agents