5 -year complex clinical and histopathological follow-up of a case of early gastric carcinoma (signet ring cells type)

J Med Life. 2016 Jul-Sep;9(3):291-293.

Abstract

The paper presents the case of a male patient, hospitalized for acute abdomen due to perforated callous ulcer. Though the clinical appearance suggested a benign pathology, the histopathological exam of the resection piece showed multicentric early gastric carcinoma, signet ring cell type. At the patient's request, total gastrectomy was not performed, a conservative solution being chosen instead. Superior digestive endoscopy with biopsy and oncological dispensarization was performed one month after surgery, then at every 6 months. After 2 years of benign results, the histopathological exam revealed the presence of malign singlet ring cells in the bioptic specimen. Respecting the patient's option of preserving a good quality of life, subtotal gastrectomy with Pean type gastroenteroanastomosis was performed followed by postoperatory chemotherapy. Endoscopic and oncological follow-up were performed at every six months for another 3 years (up to present), and the evolution was favorable with no local or metastatic recurrence. Histopathological examination was of great help in the surgical management of this case, allowing a fortunate early diagnosis, a conservative surgical approach, and the preserving of a good quality of life.

Keywords: early gastric carcinoma; histopathology; multifocal; signet ring cell; surgery.

Publication types

  • Case Reports

MeSH terms

  • Early Diagnosis
  • Follow-Up Studies
  • Gastrectomy
  • Humans
  • Male
  • Middle Aged
  • Quality of Life
  • Stomach Neoplasms / pathology*
  • Stomach Neoplasms / psychology
  • Stomach Neoplasms / surgery